Role of polyhydroxybutyrate in mitochondrial calcium uptake
نویسندگان
چکیده
منابع مشابه
Mitochondrial calcium uptake.
Calcium (Ca(2+)) uptake into the mitochondrial matrix is critically important to cellular function. As a regulator of matrix Ca(2+) levels, this flux influences energy production and can initiate cell death. If large, this flux could potentially alter intracellular Ca(2+) ([Ca(2+)]i) signals. Despite years of study, fundamental disagreements on the extent and speed of mitochondrial Ca(2+) uptak...
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The mitochondrial calcium uptake 1 (MICU1) is a regulatory subunit of the mitochondrial calcium uniporter that plays an important role in calcium sensing. It contains two EF-hand domains that are well conserved across diverse species from protozoa to plants and metazoans. The loss of MICU1 function in mammals is attributed to several neurological disorders that involve movement dysfunction. The...
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ژورنال
عنوان ژورنال: Cell Calcium
سال: 2013
ISSN: 0143-4160
DOI: 10.1016/j.ceca.2013.04.006